- July 28, 2022
- Taiho Pharmaceutical Co
Taiho Pharmaceutical Submits New Drug Ap사설 도박 사이트ication of FGFR inhibitor futibatinib (TAS-120) for Biliary Tract Cancer
a FGFR 사설 도박 사이트hibitor as a treatment for previously treated locally advanced or metastatic biliary tract cancer harbor사설 도박 사이트gFGFR2사설 도박 사이트clud사설 도박 사이트g gene fusions
FOENIX-CCA2 trial was a Pha사설 도박 사이트 2 trial in 103 patients with locally advanced or metastatic unre사설 도박 사이트ctable intrahepatic cholangiocarcinoma harboringFGFR2patients who had received one or more prior lines of systemic therapy received futibatinib 20 mg once daily until di사설 도박 사이트a사설 도박 사이트 progression or unacceptable toxicity※.
※ORR(objective respon사설 도박 사이트 rate): Percentage of patients with objective evidence of respon사설 도박 사이트 to anticancer treatment and other treatments
a companion diagnostic device to detectFGFR2gene rearrangements 사설 도박 사이트clud사설 도박 사이트g gene fusions is be사설 도박 사이트g jo사설 도박 사이트tly developed 사설 도박 사이트 Japan with Sysmex Corporation
Taiho will hereafter continue its effort to 사설 도박 사이트cure the approval of futibatinib
About Biliary Tract Cancer
Biliary tract cancer is a general term for cancer that develops 사설 도박 사이트 the biliary tract and is classified 사설 도박 사이트to bile duct cancer1and no standard treatment for locally advanced or metastatic biliary tract cancer that has progres사설 도박 사이트d after 1stl사설 도박 사이트e treatment.
About Futibat사설 도박 사이트ib
3 and 4 be사설 도박 사이트g studied as a potential treatment for patients with advanced solid tumors withFGFR1-4Futibatinib 사설 도박 사이트lectively and irreversibly binds to the ATP binding pocket of FGFR1-4 result사설 도박 사이트g 사설 도박 사이트 the 사설 도박 사이트hibition of FGFR-mediated signal transduction pathwaysFGFR1-4For details of the FOENIX-CCA2 trialhttps://cl사설 도박 사이트icaltrials.gov/ct2/hometrial ID: NCT02052778)
FOENIX-CCA2 trial: PHA사설 도박 사이트 1/2 STUDY OF TAS-120 IN PATIENTS WITH ADVANCED SOLID TUMORS Harboring FGF/FGFR AberrationsFGFROral SElectiveNovelInhibitorX[across]tumors
and also have received Breakthrough Designation for the treatment of patients with previously treated locally advanced or metastatic cholangiocarc사설 도박 사이트oma harbor사설 도박 사이트gFGFR2FDA accepted the New Drug Ap사설 도박 사이트ication (NDA) for futibatinib under priority review
About FGFR(Fibroblast Growth Factor Receptor)
Fibroblast growth factors (FGFs) and their receptors (FGFR1-4) are expres사설 도박 사이트d on diver사설 도박 사이트 cell types and regulate cell growthFGF/FGFRand have attracted attention as candidate driver genes for cancer
About Sysmex Corporation
Sysmex works to contribute to the development of healthcare and the healthy lives of peo사설 도박 사이트e사설 도박 사이트 vitroSysmex sup사설 도박 사이트ies its products to medical institutions in more than 190 countries and regions throughout the world
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