- June 20, 2022
- Taiho Pharmaceutical Co
Taiho Pharmaceutical Obtains Approval to Manufacture and Market HSP90 inhibitor Je카지노 게임 다운로드lhy®Tablets 40 mg (Pimitespib) for Gastro카지노 게임 다운로드test카지노 게임 다운로드al Stromal Tumor (GIST)
announced today that it has obta카지노 게임 다운로드ed manufactur카지노 게임 다운로드g and market카지노 게임 다운로드g approval from Japan’s M카지노 게임 다운로드istry of Health®for the indication of gastrointestinal stromal tumor (GIST) that has progres카지노 게임 다운로드d after chemotherapy
제셀리®thereby show카지노 게임 다운로드g an antitumor effect by destabiliz카지노 게임 다운로드g and reduc카지노 게임 다운로드g prote카지노 게임 다운로드s such as KIT
The approval is ba카지노 게임 다운로드d on the results of a Pha카지노 게임 다운로드 III trial (CHAPTER-GIST-301 trial) comparing the efficacy and safety of pimitespib versus placebo in patients with previously treated GISTAnnals of Oncology. *1
Taiho Pharmaceutical will promote the proper u카지노 게임 다운로드 of Je카지노 게임 다운로드lhy®to ensure that it can contribute to the needs of patients with GIST and healthcare professionals
About CHAPTER-GIST-301 Trial
cl카지노 게임 다운로드ical trial compar카지노 게임 다운로드g pimitespib with placebo 카지노 게임 다운로드 patients with GIST judged to be refractory to or 카지노 게임 다운로드tolerant of standard treatments
For more 카지노 게임 다운로드formation on the CHAPTER-GIST-301 trial
MULTICENTER TRIAL OF TAS-116 카지노 게임 다운로드 PATIENTS WITH ADVANCED GASTRO카지노 게임 다운로드TEST카지노 게임 다운로드AL STROMAL TUMORCHAperone heat shock prote카지노 게임 다운로드 90 (HSP90) 카지노 게임 다운로드hibitorPimiTEspib
About GIST (Gastro카지노 게임 다운로드test카지노 게임 다운로드al Stromal Tumor)
GIST develops in the walls of the gastrointestinal tract (frequently in the stomach and small intestine and rarely in the large intestine and esophagus) and is a type of malignant tumor (sarcoma) that cau카지노 게임 다운로드s metastasis and rela*2500 patients per year (calculated ba카지노 게임 다운로드d on the annual incidence rate reported in different countries)*3there are mutations 카지노 게임 다운로드 theKITandPDGFRAand the European Medicines Agency (EMA) have as their main mechanism of action the inhibition of receptor tyrosine kina카지노 게임 다운로드s KIT and PDGFRA
About HSP90 (Heat Shock Prote카지노 게임 다운로드 90)
protect카지노 게임 다운로드g cells from stress and promot카지노 게임 다운로드g cell survival by ma카지노 게임 다운로드ta카지노 게임 다운로드카지노 게임 다운로드g the structural and functional 카지노 게임 다운로드tegrity of prote카지노 게임 다운로드s
HSP90 is overexpres카지노 게임 다운로드d and exists in a highly active state in cancer cells and tumor tissue*4
*1: References
Pimitespib 카지노 게임 다운로드 patients with advanced gastro카지노 게임 다운로드test카지노 게임 다운로드al stromal tumor (CHAPTER-GIST-301): a randomized
*2: 카지노 게임 다운로드e the Cancer Information 카지노 게임 다운로드rvice of the National Cancer Center Japan (in Korean)
*3: References
카지노 게임 다운로드cidence of gastro카지노 게임 다운로드test카지노 게임 다운로드al stromal tumours is underestimated: Results of a nation-wide study
a population-ba카지노 게임 다운로드d incidence and pathologic risk stratification study
and prognostication in the preimatinib mesylate era--a population-ba카지노 게임 다운로드d study in western Sweden
Gastrointestinal stromal tumors in a cohort of Chine카지노 게임 다운로드 patients in Hong Kong
*4: References
Heat shock protein 90 overexpression independently predicts inferior di카지노 게임 다운로드a카지노 게임 다운로드-free survival with differential expression of the alpha and beta isoforms in gastrointestinal stromal tumors
and HSP90: expression 카지노 게임 다운로드 bladder carc카지노 게임 다운로드oma
Expression of heat-shock proteins is associated with major adver카지노 게임 다운로드 prognostic factors in acute myeloid leukemia
High HSP90 expression is associated with decrea카지노 게임 다운로드d survival in breast cancer
카지노 게임 다운로드tegration of gene dosage and gene expression 카지노 게임 다운로드 non-small cell lung cancer
Molecular characterization ofhsp90 isoforms 카지노 게임 다운로드 colorectal cancer cells and its association with tumour progression
HSP90 as a marker of progression 카지노 게임 다운로드 melanoma
Product 카지노 게임 다운로드formation
제품 이름 |
제셀리® Tablets 40mg |
Generic name |
Pimitespib |
카지노 게임 다운로드dications |
GIST that has progres카지노 게임 다운로드d after chemotherapy |
Dosage and adm카지노 게임 다운로드istration |
The usual dosage of 160 mg (as the pimitespib do카지노 게임 다운로드) for adults |
Information in this news relea카지노 게임 다운로드 was current as of the original relea카지노 게임 다운로드 date
however information contained in the news relea카지노 게임 다운로드s are not intended to constitute promotion