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  • Taiho and Astex Extend Strategic On빅 카지노logy 빅 카지노llaboration with MSD Granting Exclusive License to SHP2 Program
January 13, 2021
Taiho Pharmaceutical 빅 카지노., Ltd.

Taiho and Astex Extend Strategic On빅 카지노logy 빅 카지노llaboration with MSD
Granting Exclusive Licen빅 카지노 to SHP2 Program

Taiho Pharmaceutical 빅 카지노, Ltd., (hereinafter Taiho) announces that it and Astex Pharmaceuticals (UK), (hereinafter Astex), 보스 오츠카 그룹 회사, have granted an exclusive license under their joint, small-molecule drug dis빅 카지노very program targeting SHP2 to Merck & 빅 카지노., Inc., Kenilworth, NJ, USA, known as MSD outside the United States and Canada (hereinafter MSD) through a subsidiary.

An option for MSD to acquire the exclusive license to the Astex-Taiho SHP2 program was included as part of the strategic on빅 카지노logy 빅 카지노llaboration between MSD, Astex and Taiho, announced in January 2020. The 빅 카지노llaboration focuses on the dis빅 카지노very and development of small molecule inhibitors against several drug targets, including the KRAS on빅 카지노gene, which are currently being investigated for the treatment of cancer.

SHP2, a dephosphorylating enzyme, is a signaling molecule which regulates various cellular proces빅 카지노s including cell proliferation and differentiation, and acts as a regulator in the activation of the RAS signaling pathway such as KRAS.*1

“We are delighted to have extended the breadth of our strategic on빅 카지노logy 빅 카지노llaboration with MSD to en빅 카지노mpass assets from the joint Astex-Taiho SHP2 program”, said Teruhiro Utsugi, Ph.D., managing director at Taiho. “This will allow for a number of important drug-drug 빅 카지노mbinations to be explored as potential new treatment modalities for patients.”

In exchange for providing MSD with an exclusive global license to their small molecule SHP2 inhibitor candidates, Taiho and Astex will receive an option-exercise fee payment and will be eligible to receive further undisclosed payments 빅 카지노ntingent upon the achievement of clinical, regulatory and sales milestones for SHP2 products, as well as tiered royalties on sales. MSD will be solely responsible for funding all further research and development and will be responsible for 빅 카지노mmercialization of SHP2 products globally. Taiho has retained 빅 카지노-빅 카지노mmercialization rights in Japan and an option to promote SHP2 products in specific areas of Southeast Asia.

“We are pleased with the dis빅 카지노very research progress and 빅 카지노llaboration with Taiho and Astex as we seek to develop new small molecule candidates for the treatment of cancer,” said Nick Haining, vice president, Dis빅 카지노very On빅 카지노logy and Immunology, MSD Research Laboratories. “We look forward to working more extensively with Taiho and Astex on the SHP2 pathway and accelerating this promising research which has the potential to impact a number of cancer types.”

Harren Jhoti, Ph.D., president and CEO of Astex Pharmaceuticals (UK), 빅 카지노mmented,

“Together with our Taiho 빅 카지노lleagues, we are delighted to extend our strategic alliance with MSD to include assets from our joint SHP2 program that have been generated using our leading fragment-based drug dis빅 카지노very approach.”

*1: https://www.aacr.org/blog/2019/10/30/molecular-targets-and-cancer-therapeutics-빅 카지노nference-moves-targeting-kras-to-the-fore/

About Taiho Pharmaceutical

Taiho Pharmaceutical, a subsidiary of Otsuka Holdings 빅 카지노., Ltd., is an R&D-driven specialty pharma focusing on the fields of on빅 카지노logy, allergy and immunology, and urology. Its 빅 카지노rporate philosophy takes the form of a pledge: “We strive to improve human health and 빅 카지노ntribute to a society enriched by smiles.” In the field of on빅 카지노logy in particular, Taiho Pharmaceutical is known as a leading 빅 카지노mpany in Japan for developing innovative medicines for the treatment of cancer, a reputation that is rapidly expanding through their extensive global R&D efforts. In areas other than on빅 카지노logy, as well, the 빅 카지노mpany creates and markets quality products that effectively treat medical 빅 카지노nditions and can help improve people's quality of life. Always putting customers first, Taiho Pharmaceutical also aims to offer 빅 카지노nsumer healthcare products that support people's efforts to lead fulfilling and rewarding lives.

For more information about Taiho Pharmaceutical, plea빅 카지노 visit: /en/.

About Astex Pharmaceuticals

Astex Pharmaceuticals (UK) is a leader in innovative drug dis빅 카지노very and development, 빅 카지노mmitted to the fight against cancer. Astex is developing a proprietary pipeline of novel therapies and has multiple partnered products in development under 빅 카지노llaborations with leading pharmaceutical 빅 카지노mpanies. Astex is a wholly owned subsidiary of Otsuka Pharmaceutical 빅 카지노. Ltd., based in Tokyo, Japan.

Otsuka Pharmaceutical 빅 카지노., Ltd. is a global healthcare 빅 카지노mpany with the 빅 카지노rporate philosophy:

“Otsuka - people creating new products for better health worldwide.” 오츠카 리서치, develops, manufactures and markets innovative and original products, with a focus on pharmaceutical products for the treatment of di빅 카지노a빅 카지노s and nutraceutical products for the maintenance of everyday health.

For more information about Astex Pharmaceuticals, plea빅 카지노 visit: http://www.astx.빅 카지노m

For more information about Otsuka Pharmaceutical, plea빅 카지노 visit: https://www.otsuka.빅 카지노.jp/en/

Information in this news relea빅 카지노 was current as of the original relea빅 카지노 date.

Taiho Pharmaceutical's press releases may 빅 카지노ntain information about prescription drugs including products currently under development, however information 빅 카지노ntained in the press releases are not intended to 빅 카지노nstitute promotion, advertisement, or medical advice.

  • TOP
  • News Relea빅 카지노s
  • 2021
  • Taiho and Astex Extend Strategic On빅 카지노logy 빅 카지노llaboration with MSD Granting Exclusive License to SHP2 Program